Reishi & Antioxidants Speed Up COVID-19 Symptom Relief
- Categories:Media Center
- Time of issue:2024-05-16 16:18
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Reishi & Antioxidants Speed Up COVID-19 Symptom Relief
- Categories:Media Center
- Time of issue:2024-05-16 16:18
- Views:
The novel coronavirus has not disappeared, but rather, it has learned to strike a balance between spreading and causing harm - it can make people help it spread widely without causing severe harm. Although the influenza-like novel coronavirus is not as terrifying as it was during the pandemic, the symptoms of COVID-19 that develop after infection can still cause significant discomfort. If there is any safe and reliable method to end this discomfort earlier, it is worth considering.
The "intensity and duration of inflammation" caused by the novel coronavirus, along with the "oxidative stress" that accompanies inflammation and intensifies the inflammatory response, are the two key factors affecting the "severity of the disease" and the "speed of symptom relief". Given this, whether adopting "anti-inflammatory" and "antioxidant" dietary measures immediately upon the onset of COVID-19 symptoms can help patients alleviate symptoms and accelerate recovery has become a topic of concern in the medical community.
It seems that the effect of this "symptomatic treatment" can be expected. According to a clinical report published in the March 2023 issue of "PRILOZI" by the largest public university medical school in North Macedonia, a small country in Southern Europe, supplementing with a compound formula of anti-inflammatory and antioxidant agents, mainly Reishi extract, during the treatment of mild COVID-19 patients, indeed accelerates the recovery from COVID-19.
This small-scale clinical trial was conducted from November 2021 to January 2022, just as the Omicron variant was emerging as the dominant global strain. The trial involved 45 participants, all of whom were mild adult patients who had been diagnosed with COVID-19 and had voluntarily sought treatment at a university-affiliated clinic specializing in infectious diseases and fevers. The average age of the participants was in their early forties. The main symptoms reported included: elevated body temperature (62.2%), general discomfort (57.1%), nasal congestion (42.8%), headache (28.6%), or cough (54.76%). On the day of the initial diagnosis, two abnormalities were found in the blood test results: blood glucose levels and C-reactive protein (CRP), which is positively correlated with acute inflammation and tissue damage, both exceeded normal values.
This group of participants, none of whom had major diseases such as liver, kidney, or immune disorders, were not pregnant or breastfeeding, had never been vaccinated against COVID-19, and had not consumed any of the health ingredients in the compound preparation used in this study in the past 3 months. Of these, 30 were assigned to the treatment group, taking an additional 2 capsules of the Reishi mushroom compound preparation daily, while the remaining 15 who did not take additional supplements served as the control group. The results found that:
➤ The duration of discomfort in the treatment group lasted for an average of 9.5 days, which is more than a quarter shorter (nearly 3.5 days) compared to the control group's 13 days.
➤ On the 15th day after the initial visit, although the white blood cell count of both groups was within the normal range of 4,000 to 10,000, the treatment group's count of over 7,600 was significantly lower than the control group's count of over 9,900, and closer to the initial count of around 6,000 at the time of the first diagnosis.
➤ The Neutrophil to Lymphocyte Ratio (NLR), which is positively correlated with the severity of the disease, began to decrease in the treatment group on the 15th day after the initial visit (2.62 → 1.90), unlike the control group which remained higher than the level at the time of the first diagnosis (2.66 → 2.73).
➤ On the 15th day after the initial visit, the oxidative stress endured by the body, as well as the pro-inflammatory cytokines (TNF-α, IL-6, IL-8) induced in the early stages of infection, were significantly lower in the treatment group compared to the control group (as shown in the figure below).
The degree of improvement in oxidative stress and inflammatory response in mild COVID-19 patients 15 days after their initial visit: The treatment group, which supplemented with a compound preparation including Reishi mushroom daily, was significantly better than the control group that did not supplement. (The p-values in the figure are all less than 0.05, indicating a significant difference between the treatment group and the control group.)
In other words, regardless of whether the compound preparation including Reishi mushroom was supplemented, the mild COVID-19 patients in this study did not worsen or require hospitalization during the half-month follow-up period, and related symptoms were also alleviated. The two abnormal indicators at the time of the initial visit eventually returned to normal, and most of the blood test results showed no significant difference. However, the duration of inflammation in the body, the level of oxidative stress, and the degree of white blood cell mobilization would have significant differences depending on whether the body's antioxidant and anti-inflammatory capabilities were enhanced. This is reflected in the speed at which related symptoms subside.
Therefore, researchers believe that immediately adopting "anti-inflammatory" and "antioxidant" dietary measures upon infection with COVID-19 is indeed meaningful for patients, and this approach is also applicable to other viral infections that cause acute inflammation.
This study, based on the idea of "unity is strength," combines Reishi mushroom extract with a variety of ingredients with antioxidant and anti-inflammatory activities to form a compound preparation for research. These ingredients can serve as dietary references for us the next time we inadvertently become targets, such as consuming more fruits rich in resveratrol like blueberries, grapes, cranberries, tomatoes rich in lycopene, and cruciferous vegetables rich in sulforaphane (such as broccoli, cabbage, baby bok choy, Chinese cabbage, rapeseed, and Chinese kale).
Of course, what we must not forget is the Reishi mushroom extract that is "uniform in provenance, organically grown, standardized in extraction process, complete in active ingredients, and stable in quality," because such Reishi mushroom can not only provide antioxidant and anti-inflammatory effects but also enhance antiviral immunity, and can protect the brain, heart, liver, spleen, lungs, and kidneys under viral attack and drug action.
Of course, the best way is still to prevent problems before they occur. After all, "an ounce (28.35 grams) of gold in prevention is worth a pound (454 grams) of gold in treatment." Rather than suffering from infection and then repairing the damage at a high cost, it is better to eat the right food and consume the right Reishi mushroom at a lower cost on a regular basis to cultivate a good physique that is not easily invaded by viruses.
References: Dragica Zendelovska, et al.Effect of Supplemental Antioxidant-Based Therapy on the Oxidative Stress Level in COVID-19 Patients. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2023 Mar 29;44(1):7-16. doi: 10.2478/prilozi-2023-0002.
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★ The original manuscript of this article was authored in Chinese by Wu Tingyao and subsequently translated into English by Alfred Liu. In the event of any inconsistencies between the English translation and the original Chinese text, the latter shall take precedence. For any queries, pls reach out to the original author, Ms. Wu Tingyao.


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