The acquisition of patent certificates is an important criterion for measuring the competitiveness of an enterprise.

 

Having devoted over thirty years to the field of Reishi-oriented health, GanoHerb has consistently demonstrated its strength. It has obtained 39 patents, among which 10 are anti-tumor patents involving Ganoderma lucidum spore oil, Ganoderma extracts...

 

Now, you will be briefed on five selected patents that embody the research strength of GanoHerb!

 

1. A Ganoderma-based Anti-tumor Softgel and Its Preparation Method (Chinese Invention Patent: ZL201510580594.2)

 

This health supplement is prepared from Ganoderma lucdum spore oil, Ganoderma lucidum extract, Ganoderma sinense extract, and gelatin.

 

It concentrates the essence of Ganoderma, incorporating various bioactive substances of Ganoderma. Animal experiments have demonstrated that this product possesses anti-tumor properties and boosts the immune system.

 

 

2. A Component of Anti-tumor Activity in Ganoderma lucidum Spore Oil and Its Preparation Method (Chinese Invention Patent: ZL201310043010.9)

 

The composition of Ganoderma lucidum spore oil is complex, and identifying components with stronger anti-tumor bioactivity has been a focus of research in the scientific community.

 

This invention utilizes sporoderm-broken Ganoderma lucidum spore powder as raw material to extract, concentrate, and freeze-dry the spore oil, obtaining an anti-tumor compound. This compound can inhibit the growth of tumor cells both in vitro and in vivo, with a tumor inhibition rate exceeding 56.3%.

 

3. A Ganoderma Extract Inhibiting Tumor Metastasis (Chinese Invention Patent: ZL202211621339.4)

 

The Ganoderma extract obtained in this invention has a β-glucan content of ≥15%, an acidic triterpene content of ≥10%, a neutral triterpene content of ≥5%, with a yield controlled between 7% to 8%, preventing the inclusion of useless impurities in the Ganoderma extract.

 

The prepared Ganoderma extract, by activating caspase 3 and cleaving the substrate protein gasdermin E (GSDME) to induce cell membrane pore formation, promotes pyroptosis, leading to the formation of intracellular vesicles. This inhibits proliferation, migration, and invasion of tumor cells during metastasis.

 

4. A Method for Preparing Ganoderma Polysaccharides with High Anti-tumor Activity (Chinese Invention Patent: ZL201810425646.2)

 

Traditional methods for preparing Ganoderma polysaccharide extracts suffer from issues such as high impurity levels, low effective content, solvent residues, and high production costs.

 

This invention utilizes Reishi raw materials and employs techniques including pulverization, high-pressure supercritical CO₂ extraction, and vacuum concentration to obtain light brown Ganoderma polysaccharides. The extraction and separation methods are simple and suitable for industrial production. The resulting Ganoderma polysaccharide extract exhibits potent anti-tumor activity.

 

5. A Method for Separating and Preparing Anti-tumor Components Ganoderic Acid C1 and Ganoderic Acid F (Chinese Invention Patent: ZL201310712528.7)

 

This invention involves a method for isolating and preparing high-purity anti-tumor components, Ganoderic Acid C1 and Ganoderic Acid F, from Ganoderma alcohol extracts.

 

Modern pharmacological studies have demonstrated that ganoderic acids possess various pharmacological effects including anti-tumor, hepatoprotective, hypoglycemic, angiotensin-converting enzyme inhibition, and antioxidant properties. Among them, Ganoderic Acid C1 and Ganoderic Acid F exhibit significant efficacy against tumors.

In addition, GanoHerb has also obtained the following patents related to tumors:

A method for extracting subcritical water extracts and isolating Ganoderma triterpenes (Chinese Invention Patent: ZL 202010401445.6), A triterpene compound and its preparation method and pharmaceutical use (Chinese Invention Patent: ZL 201510192080.X), A new Ganoderma triterpene and its preparation method and pharmaceutical use (Chinese Invention Patent: ZL 201510191378.9), A new compound isolated from Ganoderma and its preparation method and pharmaceutical use (Chinese Invention Patent: ZL 201110200649.4) ... With strong R&D capabilities, GanoHerb’s patents continue to be updated!

 

Where does the formidable "research strength" of GanoHerb come from? It comes from the support of four major research and innovation platforms: the "National Edible Fungi Processing Technology R&D Center," the "National-Local Joint Engineering Research Center for Medicinal Fungi Cultivation and Deep Processing," academician workstations, and postdoctoral research workstations. In addition, through strong collaborations with renowned domestic and international universities and research institutions, a continuous influx of "research strength" is provided to GanoHerb, helping to produce more effective and high-quality Ganoderma products. This contributes to realizing GanoHerb's vision of using Ganoderma for the health and well-being of people worldwide.